Enhancing DPYSL3 gene expression via a promoter-targeted small activating RNA approach suppresses cancer cell motility and metastasis

To explore a novel strategy in suppressing tumor metastasis, we took the advantage of a recent RNA activation (RNAa) theory and used small double-strand RNA molecules, termed as small activating RNAs (saRNA) that are complimentary to target gene promoter, to enhance transcription of metastasis suppr...

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Detalles Bibliográficos
Autores principales: Li, Changlin, Jiang, Wencong, Hu, Qingting, Li, Long-cheng, Dong, Liang, Chen, Ruibao, Zhang, Yinghong, Tang, Yuzhe, Thrasher, J. Brantley, Liu, Chang-Bai, Li, Benyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008410/
https://www.ncbi.nlm.nih.gov/pubmed/27014974
http://dx.doi.org/10.18632/oncotarget.8290

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