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Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis

OBJECTIVE: There is increasing evidence supporting the role of platelets in atherosclerotic vascular disease. The G-protein-coupled receptor P2Y(12) is a central mediator of platelet activation and aggregation but has also been linked to platelet-independent vascular disease. Ticagrelor is an oral P...

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Detalles Bibliográficos
Autores principales: Preusch, Michael R, Rusnak, Jonas, Staudacher, Kathrin, Mogler, Carolin, Uhlmann, Lorenz, Sievers, Philipp, Bea, Florian, Katus, Hugo A, Blessing, Erwin, Staudacher, Ingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008449/
https://www.ncbi.nlm.nih.gov/pubmed/27616880
http://dx.doi.org/10.2147/DDDT.S105718