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Ticagrelor promotes atherosclerotic plaque stability in a mouse model of advanced atherosclerosis
OBJECTIVE: There is increasing evidence supporting the role of platelets in atherosclerotic vascular disease. The G-protein-coupled receptor P2Y(12) is a central mediator of platelet activation and aggregation but has also been linked to platelet-independent vascular disease. Ticagrelor is an oral P...
Autores principales: | Preusch, Michael R, Rusnak, Jonas, Staudacher, Kathrin, Mogler, Carolin, Uhlmann, Lorenz, Sievers, Philipp, Bea, Florian, Katus, Hugo A, Blessing, Erwin, Staudacher, Ingo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008449/ https://www.ncbi.nlm.nih.gov/pubmed/27616880 http://dx.doi.org/10.2147/DDDT.S105718 |
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