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Genome-wide DNA methylation profiling and its involved molecular pathways from one individual with thyroid malignant/benign tumor and hyperplasia: A case report

BACKGROUND: During development, methylation permanently changes gene activity, while aberrant gene methylation is key to human tumorigenesis. Gene methylation is an epigenetic event leading to gene silencing and some tumor suppressor genes that are aberrantly methylated in both thyroid cancer and be...

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Detalles Bibliográficos
Autores principales: Cai, Liang-Liang, Liu, Guo-Yan, Tzeng, Chi-Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008583/
https://www.ncbi.nlm.nih.gov/pubmed/27583899
http://dx.doi.org/10.1097/MD.0000000000004695

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