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The CYP19A1 rs3751592 variant confers susceptibility to Alzheimer disease in the Chinese Han population

BACKGROUND: The CYP19A1 enzyme (aromatase) encoded by the cytochrome P450 (CYP) 19A1 gene influences the final step in the biosynthesis of estrogen, which has been associated with Alzheimer disease (AD). It is possible that genetic polymorphisms in CYP19A1 could influence the risk of AD by altering...

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Detalles Bibliográficos
Autores principales: Zheng, Jiaqiang, Yan, Huacheng, Shi, Lei, Kong, Yanying, Zhao, Yongpan, Xie, Li, Li, Jian, Huang, Mukun, Li, Jin, Zhao, Shujin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008603/
https://www.ncbi.nlm.nih.gov/pubmed/27583919
http://dx.doi.org/10.1097/MD.0000000000004742