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C5a Induces the Synthesis of IL-6 and TNF-α in Rat Glomerular Mesangial Cells through MAPK Signaling Pathways

Inflammatory response has been reported to contribute to the renal lesions in rat Thy-1 nephritis (Thy-1N) as an animal model of human mesangioproliferative glomerulonephritis (MsPGN). Besides C5b-9 complex, C5a is also a potent pro-inflammatory mediator and correlated to severity of various nephrit...

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Detalles Bibliográficos
Autores principales:	Ji, Mingde, Lu, Yanlai, Zhao, Chenhui, Gao, Wenxing, He, Fengxia, Zhang, Jing, Zhao, Dan, Qiu, Wen, Wang, Yingwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008626/ https://www.ncbi.nlm.nih.gov/pubmed/27583546 http://dx.doi.org/10.1371/journal.pone.0161867

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