Cargando…

C5a Induces the Synthesis of IL-6 and TNF-α in Rat Glomerular Mesangial Cells through MAPK Signaling Pathways

Inflammatory response has been reported to contribute to the renal lesions in rat Thy-1 nephritis (Thy-1N) as an animal model of human mesangioproliferative glomerulonephritis (MsPGN). Besides C5b-9 complex, C5a is also a potent pro-inflammatory mediator and correlated to severity of various nephrit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Mingde, Lu, Yanlai, Zhao, Chenhui, Gao, Wenxing, He, Fengxia, Zhang, Jing, Zhao, Dan, Qiu, Wen, Wang, Yingwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008626/ https://www.ncbi.nlm.nih.gov/pubmed/27583546 http://dx.doi.org/10.1371/journal.pone.0161867

Ejemplares similares

TSP-1 promotes glomerular mesangial cell proliferation and extracellular matrix secretion in Thy-1 nephritis rats()
por: Qiu, Wen, et al.
Publicado: (2011)

Sublytic C5b‐9 induces proliferation of glomerular mesangial cells via ERK5/MZF1/RGC‐32 axis activated by FBXO28‐TRAF6 complex
por: Yu, Tianyi, et al.
Publicado: (2019)

Modulation of IL-6 Expression by KLF4-Mediated Transactivation and PCAF-Mediated Acetylation in Sublytic C5b-9-Induced Rat Glomerular Mesangial Cells
por: Xia, Lu, et al.
Publicado: (2022)

KLF6 Acetylation Promotes Sublytic C5b-9-Induced Production of MCP-1 and RANTES in Experimental Mesangial Proliferative Glomerulonephritis
por: Yu, Tianyi, et al.
Publicado: (2020)

NAD(+) Anabolism Disturbance Causes Glomerular Mesangial Cell Injury in Diabetic Nephropathy
por: Li, Xue, et al.
Publicado: (2022)

Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis
por: Xie, Mengxiao, et al.
Publicado: (2021)

Editorial: Interactions Between Podocytes, Mesangial Cells, and Glomerular Endothelial Cells in Glomerular Diseases
por: Imig, John D., et al.
Publicado: (2022)

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin α5 in the glomerular basement membrane
por: Kikkawa, Yamato, et al.
Publicado: (2003)

Pathophysiology of mesangial expansion in diabetic nephropathy: mesangial structure, glomerular biomechanics, and biochemical signaling and regulation
por: Thomas, Haryana Y., et al.
Publicado: (2022)

Impaired Expression of MAPK Is Associated with the Downregulation of TNF-α, IL-6, and IL-10 in Mycobacterium abscessus Lung Disease
por: Sim, Yun Su, et al.
Publicado: (2012)

MicroRNA-98-5p inhibits human mesangial cell proliferation and TNF-α and IL-6 secretion by targeting BTB and CNC homology 1
por: Du, Yong, et al.
Publicado: (2021)

Changes in TNF-α, IL-6, IL-10 and VEGF in rats with ARDS and the effects of dexamethasone
por: Qin, Mengting, et al.
Publicado: (2019)

TNF-α, TNF-β, IL-6, and IL-10 Polymorphisms in Patients with Lung Cancer
por: Seifart, Carola, et al.
Publicado: (2005)

Homocysteine-induced macrophage inflammatory protein-2 production by glomerular mesangial cells is mediated by PI3 Kinase and p38 MAPK
por: Shastry, Suresh, et al.
Publicado: (2009)

Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice
por: Li, Weizu, et al.
Publicado: (2017)

Effects of paraquat on IL-6 and TNF-α in macrophages
por: Huang, Jie, et al.
Publicado: (2019)

A novel recombinant DNA vaccine encoding Mycobacterium tuberculosis ESAT-6 and FL protects against Mycobacterium tuberculosis challenge in mice
por: Jiang, Qingtao, et al.
Publicado: (2013)

Effects of Dangguibuxue decoction on rat glomerular mesangial cells cultured under high glucose conditions
por: Ren, Xiao-Dan, et al.
Publicado: (2017)

LPS- and LTA-Induced Expression of IL-6 and TNF-α in Neonatal and Adult Blood: Role of MAPKs and NF-κB
por: Koch, Lutz, et al.
Publicado: (2014)

Effects of ulinastatin and docataxel on breast tumor growth and expression of IL-6, IL-8, and TNF-α
por: Zhao, Xiaoliang, et al.
Publicado: (2011)

Author Correction: A novel recombinant DNA vaccine encoding Mycobacterium tuberculosis ESAT-6 and FL protects against Mycobacterium tuberculosis challenge in mice
por: Jiang, Qingtao, et al.
Publicado: (2022)

Corosolic acid inhibits the proliferation of glomerular mesangial cells and protects against diabetic renal damage
por: Li, Xiao-Qiang, et al.
Publicado: (2016)

Effect of recombinant Hepatitis B virus on human glomerular mesangial cell apoptosis
por: Wang, Yiguo, et al.
Publicado: (2014)

Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival
por: Phua, Yu Leng, et al.
Publicado: (2015)

Huangqi Guizhi Wuwu Decoction can prevent and treat oxaliplatin-induced neuropathic pain by TNFα/IL-1β/IL-6/MAPK/NF-kB pathway
por: Li, Mingzhu, et al.
Publicado: (2022)

Effect of dexmedetomidine anesthesia on perioperative levels of TNF-α and IL-6 in patients with ovarian cancer
por: Liu, Maodong, et al.
Publicado: (2019)

THE GLOMERULAR MESANGIUM : III. ACUTE IMMUNE MESANGIAL INJURY: A NEW MODEL OF GLOMERULONEPHRITIS
por: Mauer, S. Michael, et al.
Publicado: (1973)

Sirolimus Enhances Cyclosporine A-Induced Cytotoxicity in Human Renal Glomerular Mesangial Cells
por: O'Connell, Séin, et al.
Publicado: (2012)

Influence of Acute High Glucose on Protein Abundance Changes in Murine Glomerular Mesangial Cells
por: Barati, Michelle T., et al.
Publicado: (2016)

Caveolin-1 is involved in high glucose accelerated human glomerular mesangial cell senescence
por: Feng, Xin, et al.
Publicado: (2017)

Polyethylene Glycol 3350 Crystal Nephropathy in Association With Glomerular Mesangial Immunoglobin A Deposition
por: Aly, Rasha, et al.
Publicado: (2022)

The synthetic triterpenoid, RTA405, increases glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells
por: Ding, Yanfeng, et al.
Publicado: (2012)

AngII-induced glomerular mesangial cell proliferation inhibited by losartan via changes in intracellular calcium ion concentration
por: Qiu, Guoying, et al.
Publicado: (2013)

Effect of revascularization on IL-6 and TNF-α in patients with thromboangiitis obliterans
por: Wu, Shifeng, et al.
Publicado: (2018)

Paraquat-Induced Reactive Oxygen Species Inhibit Neutrophil Apoptosis via a p38 MAPK/NF-κB–IL-6/TNF-α Positive-Feedback Circuit
por: Wang, Xiaolong, et al.
Publicado: (2014)

Knockdown of FOXO6 inhibits cell proliferation and ECM accumulation in glomerular mesangial cells cultured under high glucose condition
por: Wang, Yunqian, et al.
Publicado: (2019)

Serum concentration of IL-6, IL-2, TNF-α, and IFNγ in Vitiligo patients
por: Singh, Suman, et al.
Publicado: (2012)

IL-6 Induction by TNFα and IL-1β in an Osteoblast-Like Cell Line
por: Confalone, Elena, et al.
Publicado: (2010)

Assessment of IL-6, IL-8 and TNF-α levels in the gingival tissue of patients with periodontitis
por: NOH, MIN KI, et al.
Publicado: (2013)

Salivary IL-8, IL-6 and TNF-α as Potential Diagnostic Biomarkers for Oral Cancer
por: Sahibzada, Haafsa Arshad, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gq0iirrfob8isdns93o37lb9rl