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Phosphatidylserine and Phosphatidylethanolamine Bind to Protein Z Cooperatively and with Equal Affinity

Protein Z (PZ) is an anticoagulant that binds with high affinity to Protein Z-dependent protease inhibitor (ZPI) and accelerates the rate of ZPI-mediated inhibition of factor Xa (fXa) by more than 1000-fold in the presence of Ca(2+) and phospholipids. PZ promotion of the ZPI-fXa interaction results...

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Detalles Bibliográficos
Autores principales:	Sengupta, Tanusree, Manoj, Narayanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008636/ https://www.ncbi.nlm.nih.gov/pubmed/27584039 http://dx.doi.org/10.1371/journal.pone.0161896

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