Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice

BACKGROUND: The aim of this study was to investigate the variety of plasma contents of membrane glycolipids in 65 gastrointestinal tumors and 31 transplant hepatomas in mice. MATERIAL/METHODS: The experimental model was a transplantable murine hepatoma. Experimental mice were divided into 3 groups....

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Detalles Bibliográficos
Autores principales: Lv, Jun, Lv, Can Qun, Wang, Bo-Liang, Mei, Ping, Xu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Animal Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008736/
https://www.ncbi.nlm.nih.gov/pubmed/27554918
http://dx.doi.org/10.12659/MSMBR.899635
Descripción
Sumario:BACKGROUND: The aim of this study was to investigate the variety of plasma contents of membrane glycolipids in 65 gastrointestinal tumors and 31 transplant hepatomas in mice. MATERIAL/METHODS: The experimental model was a transplantable murine hepatoma. Experimental mice were divided into 3 groups. RESULTS: The LSA and TSA content in the 2 groups were significantly difference (p<0.01), and were significantly lower in the therapeutic group than in the control group (p<0.01). CONCLUSIONS: These results indicate that membrane glycolipids index LSA and TSA are sensitive markers in gastrointestinal tumors. In the transplanted hepatomas in mice, they may be considered as ancillary indicators for judging the therapeutic effect of hepatoma.

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