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Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice
BACKGROUND: The aim of this study was to investigate the variety of plasma contents of membrane glycolipids in 65 gastrointestinal tumors and 31 transplant hepatomas in mice. MATERIAL/METHODS: The experimental model was a transplantable murine hepatoma. Experimental mice were divided into 3 groups....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008736/ https://www.ncbi.nlm.nih.gov/pubmed/27554918 http://dx.doi.org/10.12659/MSMBR.899635 |
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author | Lv, Jun Lv, Can Qun Wang, Bo-Liang Mei, Ping Xu, Lei |
author_facet | Lv, Jun Lv, Can Qun Wang, Bo-Liang Mei, Ping Xu, Lei |
author_sort | Lv, Jun |
collection | PubMed |
description | BACKGROUND: The aim of this study was to investigate the variety of plasma contents of membrane glycolipids in 65 gastrointestinal tumors and 31 transplant hepatomas in mice. MATERIAL/METHODS: The experimental model was a transplantable murine hepatoma. Experimental mice were divided into 3 groups. RESULTS: The LSA and TSA content in the 2 groups were significantly difference (p<0.01), and were significantly lower in the therapeutic group than in the control group (p<0.01). CONCLUSIONS: These results indicate that membrane glycolipids index LSA and TSA are sensitive markers in gastrointestinal tumors. In the transplanted hepatomas in mice, they may be considered as ancillary indicators for judging the therapeutic effect of hepatoma. |
format | Online Article Text |
id | pubmed-5008736 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-50087362016-09-14 Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice Lv, Jun Lv, Can Qun Wang, Bo-Liang Mei, Ping Xu, Lei Med Sci Monit Basic Res Animal Studies BACKGROUND: The aim of this study was to investigate the variety of plasma contents of membrane glycolipids in 65 gastrointestinal tumors and 31 transplant hepatomas in mice. MATERIAL/METHODS: The experimental model was a transplantable murine hepatoma. Experimental mice were divided into 3 groups. RESULTS: The LSA and TSA content in the 2 groups were significantly difference (p<0.01), and were significantly lower in the therapeutic group than in the control group (p<0.01). CONCLUSIONS: These results indicate that membrane glycolipids index LSA and TSA are sensitive markers in gastrointestinal tumors. In the transplanted hepatomas in mice, they may be considered as ancillary indicators for judging the therapeutic effect of hepatoma. International Scientific Literature, Inc. 2016-08-24 /pmc/articles/PMC5008736/ /pubmed/27554918 http://dx.doi.org/10.12659/MSMBR.899635 Text en © Med Sci Monit, 2016 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) |
spellingShingle | Animal Studies Lv, Jun Lv, Can Qun Wang, Bo-Liang Mei, Ping Xu, Lei Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice |
title | Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice |
title_full | Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice |
title_fullStr | Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice |
title_full_unstemmed | Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice |
title_short | Membrane Glycolipids Content Variety in Gastrointestinal Tumors and Transplantable Hepatomas in Mice |
title_sort | membrane glycolipids content variety in gastrointestinal tumors and transplantable hepatomas in mice |
topic | Animal Studies |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008736/ https://www.ncbi.nlm.nih.gov/pubmed/27554918 http://dx.doi.org/10.12659/MSMBR.899635 |
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