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Mogrol Derived from Siraitia grosvenorii Mogrosides Suppresses 3T3-L1 Adipocyte Differentiation by Reducing cAMP-Response Element-Binding Protein Phosphorylation and Increasing AMP-Activated Protein Kinase Phosphorylation
This study investigated the effects of mogrol, an aglycone of mogrosides from Siraitia grosvenorii, on adipogenesis in 3T3-L1 preadipocytes. Mogrol, but not mogrosides, suppressed triglyceride accumulation by affecting early (days 0–2) and late (days 4–8), but not middle (days 2–4), differentiation...
Autores principales: | Harada, Naoki, Ishihara, Mikako, Horiuchi, Hiroko, Ito, Yuta, Tabata, Hiromitsu, Suzuki, Yasushi A., Nakano, Yoshihisa, Yamaji, Ryoichi, Inui, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008739/ https://www.ncbi.nlm.nih.gov/pubmed/27583359 http://dx.doi.org/10.1371/journal.pone.0162252 |
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