Higher LPA2 and LPA6 mRNA Levels in Hepatocellular Carcinoma Are Associated with Poorer Differentiation, Microvascular Invasion and Earlier Recurrence with Higher Serum Autotaxin Levels

Hepatocellular carcinoma (HCC) commonly develops in patients with liver fibrosis; in these patients, the blood levels of lysophosphatidic acid (LPA) and its generating enzyme autotaxin (ATX) increase with the liver fibrosis stage. We aimed to examine the potential relevance of ATX and LPA in HCC. Fi...

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Detalles Bibliográficos
Autores principales: Enooku, Kenichiro, Uranbileg, Baasanjav, Ikeda, Hitoshi, Kurano, Makoto, Sato, Masaya, Kudo, Hiroki, Maki, Harufumi, Koike, Kazuhiko, Hasegawa, Kiyoshi, Kokudo, Norihiro, Yatomi, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008774/
https://www.ncbi.nlm.nih.gov/pubmed/27583415
http://dx.doi.org/10.1371/journal.pone.0161825

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