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IL-28B Genetic Variants Determine the Extent of Monocyte-Induced Activation of NK Cells in Hepatitis C

BACKGROUND: Immuno-genetic studies suggest a functional link between NK cells and λ-IFNs. We recently showed that NK cells are negative for the IFN-λ receptor IFN-λR1 and do not respond to IFN-λ, suggesting a rather indirect association between IL-28B genotype and NK cell activity. METHODS: A total...

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Detalles Bibliográficos
Autores principales:	Krämer, Benjamin, Finnemann, Claudia, Sastre, Beatriz, Lutz, Philipp, Glässner, Andreas, Wolter, Franziska, Goeser, Felix, Kokordelis, Pavlos, Kaczmarek, Dominik, Nischalke, Hans-Dieter, Strassburg, Christian P., Spengler, Ulrich, Nattermann, Jacob
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008784/ https://www.ncbi.nlm.nih.gov/pubmed/27583440 http://dx.doi.org/10.1371/journal.pone.0162068

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