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Tuning PAK Activity to Rescue Abnormal Myelin Permeability in HNPP

Schwann cells in the peripheral nervous systems extend their membranes to wrap axons concentrically and form the insulating sheath, called myelin. The spaces between layers of myelin are sealed by myelin junctions. This tight insulation enables rapid conduction of electric impulses (action potential...

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Detalles Bibliográficos
Autores principales:	Hu, Bo, Arpag, Sezgi, Zhang, Xuebao, Möbius, Wiebke, Werner, Hauke, Sosinsky, Gina, Ellisman, Mark, Zhang, Yang, Hamilton, Audra, Chernoff, Jonathan, Li, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008806/ https://www.ncbi.nlm.nih.gov/pubmed/27583434 http://dx.doi.org/10.1371/journal.pgen.1006290

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