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Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells

The Suppressors of Cytokine Signalling (SOCS) proteins are negative regulators of cytokine signalling required to prevent excess cellular responses. SOCS1 and SOCS3 are essential to prevent inflammatory disease, SOCS1 by attenuating responses to IFNγ and gamma-common (γc) cytokines, and SOCS3 via re...

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Detalles Bibliográficos
Autores principales: Ushiki, Takashi, Huntington, Nicholas D., Glaser, Stefan P., Kiu, Hiu, Georgiou, Angela, Zhang, Jian-Guo, Metcalf, Donald, Nicola, Nicos A., Roberts, Andrew W., Alexander, Warren S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008821/
https://www.ncbi.nlm.nih.gov/pubmed/27583437
http://dx.doi.org/10.1371/journal.pone.0162111