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Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells
The Suppressors of Cytokine Signalling (SOCS) proteins are negative regulators of cytokine signalling required to prevent excess cellular responses. SOCS1 and SOCS3 are essential to prevent inflammatory disease, SOCS1 by attenuating responses to IFNγ and gamma-common (γc) cytokines, and SOCS3 via re...
Autores principales: | Ushiki, Takashi, Huntington, Nicholas D., Glaser, Stefan P., Kiu, Hiu, Georgiou, Angela, Zhang, Jian-Guo, Metcalf, Donald, Nicola, Nicos A., Roberts, Andrew W., Alexander, Warren S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008821/ https://www.ncbi.nlm.nih.gov/pubmed/27583437 http://dx.doi.org/10.1371/journal.pone.0162111 |
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