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Statin-induced expression change of INSIG1 in lymphoblastoid cell lines correlates with plasma triglyceride statin response in a sex-specific manner
Statins are widely prescribed to lower plasma low-density lipoprotein (LDL) cholesterol levels. They also modestly reduce plasma triglyceride (TG), an independent cardiovascular disease risk factor, in most people. The mechanism and inter-individual variability of TG statin response is poorly unders...
Autores principales: | Theusch, E, Kim, K, Stevens, K, Smith, J D, Chen, Y -D I, Rotter, J I, Nickerson, D A, Medina, M W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008997/ https://www.ncbi.nlm.nih.gov/pubmed/26927283 http://dx.doi.org/10.1038/tpj.2016.12 |
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