Controversy about the relationship between sulfonylurea use and cardiovascular events and mortality

Among a number of classes of oral antihyperglycemic drugs, sulfonylureas (SUs) demonstrating the potential effect to reduce blood glucose level have been used in a majority of patients with type 2 diabetes for many years. The pathophysiological processes by which SUs adversely induce the risk of car...

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Detalles Bibliográficos
Autores principales: Shimoda, Masashi, Kaku, Kohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009127/
https://www.ncbi.nlm.nih.gov/pubmed/27181105
http://dx.doi.org/10.1111/jdi.12494
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author Shimoda, Masashi
Kaku, Kohei
author_facet Shimoda, Masashi
Kaku, Kohei
author_sort Shimoda, Masashi
collection PubMed
description Among a number of classes of oral antihyperglycemic drugs, sulfonylureas (SUs) demonstrating the potential effect to reduce blood glucose level have been used in a majority of patients with type 2 diabetes for many years. The pathophysiological processes by which SUs adversely induce the risk of cardiovascular disease have not been fully clarified. We summarized about the relationship between SU use and cardiovascular events and mortality in patients with type 2 diabetes.[Image: see text]
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spelling pubmed-50091272016-09-12 Controversy about the relationship between sulfonylurea use and cardiovascular events and mortality Shimoda, Masashi Kaku, Kohei J Diabetes Investig Commentaries Among a number of classes of oral antihyperglycemic drugs, sulfonylureas (SUs) demonstrating the potential effect to reduce blood glucose level have been used in a majority of patients with type 2 diabetes for many years. The pathophysiological processes by which SUs adversely induce the risk of cardiovascular disease have not been fully clarified. We summarized about the relationship between SU use and cardiovascular events and mortality in patients with type 2 diabetes.[Image: see text] John Wiley and Sons Inc. 2016-03-24 2016-09 /pmc/articles/PMC5009127/ /pubmed/27181105 http://dx.doi.org/10.1111/jdi.12494 Text en © 2016 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Commentaries
Shimoda, Masashi
Kaku, Kohei
Controversy about the relationship between sulfonylurea use and cardiovascular events and mortality
title Controversy about the relationship between sulfonylurea use and cardiovascular events and mortality
title_full Controversy about the relationship between sulfonylurea use and cardiovascular events and mortality
title_fullStr Controversy about the relationship between sulfonylurea use and cardiovascular events and mortality
title_full_unstemmed Controversy about the relationship between sulfonylurea use and cardiovascular events and mortality
title_short Controversy about the relationship between sulfonylurea use and cardiovascular events and mortality
title_sort controversy about the relationship between sulfonylurea use and cardiovascular events and mortality
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009127/
https://www.ncbi.nlm.nih.gov/pubmed/27181105
http://dx.doi.org/10.1111/jdi.12494
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