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A multi-centre pilot study of iodine status in UK schoolchildren, aged 8–10 years

PURPOSE: Iodine, as an essential constituent of thyroid hormones, is required for brain development. Iodine status is low in some UK population groups, notably in teenage girls, women of childbearing age and pregnant women. We aimed to assess iodine status of UK schoolchildren as there are no data o...

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Autores principales: Bath, Sarah C., Combet, Emilie, Scully, Patrick, Zimmermann, Michael B., Hampshire-Jones, Katharine H. C., Rayman, Margaret P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009164/
https://www.ncbi.nlm.nih.gov/pubmed/26276556
http://dx.doi.org/10.1007/s00394-015-1014-y
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author Bath, Sarah C.
Combet, Emilie
Scully, Patrick
Zimmermann, Michael B.
Hampshire-Jones, Katharine H. C.
Rayman, Margaret P.
author_facet Bath, Sarah C.
Combet, Emilie
Scully, Patrick
Zimmermann, Michael B.
Hampshire-Jones, Katharine H. C.
Rayman, Margaret P.
author_sort Bath, Sarah C.
collection PubMed
description PURPOSE: Iodine, as an essential constituent of thyroid hormones, is required for brain development. Iodine status is low in some UK population groups, notably in teenage girls, women of childbearing age and pregnant women. We aimed to assess iodine status of UK schoolchildren as there are no data on children below 14 years of age. METHODS: Children (boys and girls) aged 8–10 years were recruited to a cross-sectional study from schools in three areas of the UK (Omagh, Northern Ireland; Glasgow, Scotland, and Guildford, South-East England). Spot urine samples, for measurement of urinary iodine concentration, were collected in the winter months (November 2012 to March 2013) and in the summer, in Omagh only (September 2013). A food frequency questionnaire was completed. RESULTS: A total of 168 schoolchildren provided 165 urine samples. The median urinary iodine concentration was 161 µg/L in winter samples (n = 134) and 127 µg/L in summer samples (n = 31). The median urinary iodine concentration for the whole group was 144 µg/L, weighted to account for the unequal proportion of samples from the two seasons. The children are classified as iodine-sufficient by WHO criteria (100–199 µg/L), even in the summer. Milk intake was positively associated with iodine status. CONCLUSIONS: This pilot study suggests that iodine deficiency is unlikely to be a problem in UK children aged 8–10 years. This could be a result of higher intake of milk, the principal UK dietary iodine source, in this age group than in teenagers and adults. Further assessment of iodine status in a representative sample of UK schoolchildren is required.
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spelling pubmed-50091642016-09-16 A multi-centre pilot study of iodine status in UK schoolchildren, aged 8–10 years Bath, Sarah C. Combet, Emilie Scully, Patrick Zimmermann, Michael B. Hampshire-Jones, Katharine H. C. Rayman, Margaret P. Eur J Nutr Original Contribution PURPOSE: Iodine, as an essential constituent of thyroid hormones, is required for brain development. Iodine status is low in some UK population groups, notably in teenage girls, women of childbearing age and pregnant women. We aimed to assess iodine status of UK schoolchildren as there are no data on children below 14 years of age. METHODS: Children (boys and girls) aged 8–10 years were recruited to a cross-sectional study from schools in three areas of the UK (Omagh, Northern Ireland; Glasgow, Scotland, and Guildford, South-East England). Spot urine samples, for measurement of urinary iodine concentration, were collected in the winter months (November 2012 to March 2013) and in the summer, in Omagh only (September 2013). A food frequency questionnaire was completed. RESULTS: A total of 168 schoolchildren provided 165 urine samples. The median urinary iodine concentration was 161 µg/L in winter samples (n = 134) and 127 µg/L in summer samples (n = 31). The median urinary iodine concentration for the whole group was 144 µg/L, weighted to account for the unequal proportion of samples from the two seasons. The children are classified as iodine-sufficient by WHO criteria (100–199 µg/L), even in the summer. Milk intake was positively associated with iodine status. CONCLUSIONS: This pilot study suggests that iodine deficiency is unlikely to be a problem in UK children aged 8–10 years. This could be a result of higher intake of milk, the principal UK dietary iodine source, in this age group than in teenagers and adults. Further assessment of iodine status in a representative sample of UK schoolchildren is required. Springer Berlin Heidelberg 2015-08-15 2016 /pmc/articles/PMC5009164/ /pubmed/26276556 http://dx.doi.org/10.1007/s00394-015-1014-y Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Contribution
Bath, Sarah C.
Combet, Emilie
Scully, Patrick
Zimmermann, Michael B.
Hampshire-Jones, Katharine H. C.
Rayman, Margaret P.
A multi-centre pilot study of iodine status in UK schoolchildren, aged 8–10 years
title A multi-centre pilot study of iodine status in UK schoolchildren, aged 8–10 years
title_full A multi-centre pilot study of iodine status in UK schoolchildren, aged 8–10 years
title_fullStr A multi-centre pilot study of iodine status in UK schoolchildren, aged 8–10 years
title_full_unstemmed A multi-centre pilot study of iodine status in UK schoolchildren, aged 8–10 years
title_short A multi-centre pilot study of iodine status in UK schoolchildren, aged 8–10 years
title_sort multi-centre pilot study of iodine status in uk schoolchildren, aged 8–10 years
topic Original Contribution
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009164/
https://www.ncbi.nlm.nih.gov/pubmed/26276556
http://dx.doi.org/10.1007/s00394-015-1014-y
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