Differentiation of control and ALS mutant human iPSCs into functional skeletal muscle cells, a tool for the study of neuromuscolar diseases

Amyotrophic Lateral Sclerosis (ALS) is a severe and fatal neurodegenerative disease characterized by progressive loss of motoneurons, muscle atrophy and paralysis. Recent evidence suggests that ALS should be considered as a multi-systemic disease, in which several cell types contribute to motoneuron...

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Detalles Bibliográficos
Autores principales: Lenzi, Jessica, Pagani, Francesca, De Santis, Riccardo, Limatola, Cristina, Bozzoni, Irene, Di Angelantonio, Silvia, Rosa, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009183/
https://www.ncbi.nlm.nih.gov/pubmed/27318155
http://dx.doi.org/10.1016/j.scr.2016.06.003

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