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Enhanced pinocembrin production in Escherichia coli by regulating cinnamic acid metabolism

Microbial biosynthesis of pinocembrin is of great interest in the area of drug research and human healthcare. Here we found that the accumulation of the pathway intermediate cinnamic acid adversely affected pinocembrin production. Hence, a stepwise metabolic engineering strategy was carried out aime...

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Detalles Bibliográficos
Autores principales:	Cao, Weijia, Ma, Weichao, Wang, Xin, Zhang, Bowen, Cao, Xun, Chen, Kequan, Li, Yan, Ouyang, Pingkai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009306/ https://www.ncbi.nlm.nih.gov/pubmed/27586788 http://dx.doi.org/10.1038/srep32640

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