Cargando…
3′-hydroxy-3,4,5,4′-tetramethoxystilbene, the metabolite of resveratrol analogue DMU-212, inhibits ovarian cancer cell growth in vitro and in a mice xenograft model
In screening studies, the cytotoxic activity of four metabolites of resveratrol analogue 3,4,5,4′-tetramethoxystilbene (DMU-212) against A-2780 and SKOV-3 ovarian cancer cells was investigated. The most active metabolite, 3′-hydroxy-3,4,5,4′-tetramethoxystilbene (DMU-214), was chosen for further stu...
Autores principales: | Piotrowska-Kempisty, Hanna, Ruciński, Marcin, Borys, Sylwia, Kucińska, Małgorzata, Kaczmarek, Mariusz, Zawierucha, Piotr, Wierzchowski, Marcin, Łażewski, Dawid, Murias, Marek, Jodynis-Liebert, Jadwiga |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009320/ https://www.ncbi.nlm.nih.gov/pubmed/27585955 http://dx.doi.org/10.1038/srep32627 |
Ejemplares similares
-
3,4,5,4′-trans-tetramethoxystilbene (DMU-212) modulates the activation of NF-κB, AP-1, and STAT3 transcription factors in rat liver carcinogenesis induced by initiation-promotion regimen
por: Cichocki, Michał, et al.
Publicado: (2014) -
The Effect of 3′-Hydroxy-3,4,5,4′-Tetramethoxy -stilbene, the Metabolite of the Resveratrol Analogue DMU-212, on the Motility and Proliferation of Ovarian Cancer Cells
por: Nowicki, Andrzej, et al.
Publicado: (2020) -
The Effect of 4′-hydroxy-3,4,5-trimetoxystilbene, the Metabolite of Resveratrol Analogue DMU-212, on Growth, Cell Cycle and Apoptosis in DLD-1 and LOVO Colon Cancer Cell Lines
por: Jozkowiak, Malgorzata, et al.
Publicado: (2020) -
Enhanced biological activity of liposomal methylated resveratrol analog 3′-hydroxy-3,4,5,4′-tetramethoxystilbene (DMU-214) in 3D patient-derived ovarian cancer model
por: Nowicki, Andrzej, et al.
Publicado: (2022) -
Steroidogenic activity of liposomal methylated resveratrol analog 3,4,5,4′-tetramethoxystilbene (DMU-212) in human luteinized granulosa cells in a primary three-dimensional in vitro model
por: Józkowiak, Małgorzata, et al.
Publicado: (2023)