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Peptidomimetics Based On Dehydroepiandrosterone Scaffold: Synthesis, Antiproliferation Activity, Structure-Activity Relationship, and Mechanisms

A series of novel peptidomimetics bearing dehydroepiandrosterone moiety were designed, synthesized, and evaluated for their inhibition activities against cell proliferation. According to the preliminary studies on inhibitory activities, some of the newly prepared compounds indicated significantly in...

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Detalles Bibliográficos
Autores principales: Wang, Xiaohui, Su, Haihuan, Wang, Wenda, Chen, Changshui, Cao, Xiufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009342/
https://www.ncbi.nlm.nih.gov/pubmed/27585479
http://dx.doi.org/10.1038/srep32654