Alu-miRNA interactions modulate transcript isoform diversity in stress response and reveal signatures of positive selection

Primate-specific Alus harbor different regulatory features, including miRNA targets. In this study, we provide evidence for miRNA-mediated modulation of transcript isoform levels during heat-shock response through exaptation of Alu-miRNA sites in mature mRNA. We performed genome-wide expression prof...

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Detalles Bibliográficos
Autores principales: Pandey, Rajesh, Bhattacharya, Aniket, Bhardwaj, Vivek, Jha, Vineet, Mandal, Amit K., Mukerji, Mitali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009348/
https://www.ncbi.nlm.nih.gov/pubmed/27586304
http://dx.doi.org/10.1038/srep32348

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