Cigarette smoke extract-induced p120-mediated NF-κB activation in human epithelial cells is dependent on the RhoA/ROCK pathway

Cigarette smoke exposure is a major cause of chronic obstructive pulmonary disease (COPD), but the underlying molecular inflammatory mechanisms remain poorly understood. Previous studies have found that smoke disrupts cell-cell adhesion by inducing epithelial barrier damage to the adherens junction...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Qin, Shenghui, Qin, Lingzhi, Liu, Liwei, Sun, Wenjia, Li, Xiyu, Li, Naping, Wu, Renliang, Wang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009380/
https://www.ncbi.nlm.nih.gov/pubmed/27586697
http://dx.doi.org/10.1038/srep23131

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