Identification of mutations through dominant screening for obesity using C57BL/6 substrains

The discovery of leptin substantiated the usefulness of a forward genetic approach in elucidating the molecular network regulating energy metabolism. However, no successful dominant screening for obesity has been reported, which may be due to the influence of quantitative trait loci between the scre...

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Detalles Bibliográficos
Autores principales: Hossain, Mohammad Sarowar, Asano, Fuyuki, Fujiyama, Tomoyuki, Miyoshi, Chika, Sato, Makito, Ikkyu, Aya, Kanno, Satomi, Hotta, Noriko, Kakizaki, Miyo, Honda, Takato, Kim, Staci J., Komiya, Haruna, Miura, Ikuo, Suzuki, Tomohiro, Kobayashi, Kimio, Kaneda, Hideki, Kumar, Vivek, Takahashi, Joseph S., Wakana, Shigeharu, Funato, Hiromasa, Yanagisawa, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009433/
https://www.ncbi.nlm.nih.gov/pubmed/27585985
http://dx.doi.org/10.1038/srep32453

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