An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome

Anatomical and functional brain abnormalities begin during fetal life in Down syndrome (DS). We hypothesize that novel prenatal treatments can be identified by targeting signaling pathways that are consistently perturbed in cell types/tissues obtained from human fetuses with DS and mouse embryos. We...

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Detalles Bibliográficos
Autores principales: Guedj, Faycal, Pennings, Jeroen LA, Massingham, Lauren J., Wick, Heather C., Siegel, Ashley E., Tantravahi, Umadevi, Bianchi, Diana W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009456/
https://www.ncbi.nlm.nih.gov/pubmed/27586445
http://dx.doi.org/10.1038/srep32353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009456/
https://www.ncbi.nlm.nih.gov/pubmed/27586445
http://dx.doi.org/10.1038/srep32353

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