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An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome
Anatomical and functional brain abnormalities begin during fetal life in Down syndrome (DS). We hypothesize that novel prenatal treatments can be identified by targeting signaling pathways that are consistently perturbed in cell types/tissues obtained from human fetuses with DS and mouse embryos. We...
Autores principales: | Guedj, Faycal, Pennings, Jeroen LA, Massingham, Lauren J., Wick, Heather C., Siegel, Ashley E., Tantravahi, Umadevi, Bianchi, Diana W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009456/ https://www.ncbi.nlm.nih.gov/pubmed/27586445 http://dx.doi.org/10.1038/srep32353 |
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