Interaction between interleukin-1β and type-1 cannabinoid receptor is involved in anxiety-like behavior in experimental autoimmune encephalomyelitis

BACKGROUND: Mood disorders, including anxiety and depression, are frequently diagnosed in multiple sclerosis (MS) patients, even independently of the disabling symptoms associated with the disease. Anatomical, biochemical, and pharmacological evidence indicates that type-1 cannabinoid receptor (CB1R...

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Detalles Bibliográficos
Autores principales: Gentile, Antonietta, Fresegna, Diego, Musella, Alessandra, Sepman, Helena, Bullitta, Silvia, De Vito, Francesca, Fantozzi, Roberta, Usiello, Alessandro, Maccarrone, Mauro, Mercuri, Nicola B., Lutz, Beat, Mandolesi, Georgia, Centonze, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009553/
https://www.ncbi.nlm.nih.gov/pubmed/27589957
http://dx.doi.org/10.1186/s12974-016-0682-8

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