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SPAI: an interactive platform for indel analysis
BACKGROUND: Insertions and Deletions (Indels) are the most common form of structural variation in human genome. Indels not only contribute to genetic diversity but also cause diseases. Therefore assessing indels in human genome has become an interesting topic to the research community. This increasi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009558/ https://www.ncbi.nlm.nih.gov/pubmed/27585593 http://dx.doi.org/10.1186/s12864-016-2824-x |
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author | Hasan, Mohammad Shabbir Zhang, Liqing |
author_facet | Hasan, Mohammad Shabbir Zhang, Liqing |
author_sort | Hasan, Mohammad Shabbir |
collection | PubMed |
description | BACKGROUND: Insertions and Deletions (Indels) are the most common form of structural variation in human genome. Indels not only contribute to genetic diversity but also cause diseases. Therefore assessing indels in human genome has become an interesting topic to the research community. This increasing interest on indel calling research has resulted into the development of a good number of indel calling tools. However, all of these tools are command line based and require expertise from Computer Science (CS) to execute them which makes it challenging for researchers from non-CS background. METHODS: In this paper, we describe an interactive platform named SPAI which stands for Single Platform for Analyzing Indels. RESULTS: Being a Graphical User Interface (GUI) tool, SPAI facilitates users to run several popular indel calling tools and perform several analyses on the indel calling results without knowing any command line programming. CONCLUSIONS: SPAI is written in Java and tested in Linux operating system. |
format | Online Article Text |
id | pubmed-5009558 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-50095582016-09-08 SPAI: an interactive platform for indel analysis Hasan, Mohammad Shabbir Zhang, Liqing BMC Genomics Research BACKGROUND: Insertions and Deletions (Indels) are the most common form of structural variation in human genome. Indels not only contribute to genetic diversity but also cause diseases. Therefore assessing indels in human genome has become an interesting topic to the research community. This increasing interest on indel calling research has resulted into the development of a good number of indel calling tools. However, all of these tools are command line based and require expertise from Computer Science (CS) to execute them which makes it challenging for researchers from non-CS background. METHODS: In this paper, we describe an interactive platform named SPAI which stands for Single Platform for Analyzing Indels. RESULTS: Being a Graphical User Interface (GUI) tool, SPAI facilitates users to run several popular indel calling tools and perform several analyses on the indel calling results without knowing any command line programming. CONCLUSIONS: SPAI is written in Java and tested in Linux operating system. BioMed Central 2016-08-31 /pmc/articles/PMC5009558/ /pubmed/27585593 http://dx.doi.org/10.1186/s12864-016-2824-x Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Hasan, Mohammad Shabbir Zhang, Liqing SPAI: an interactive platform for indel analysis |
title | SPAI: an interactive platform for indel analysis |
title_full | SPAI: an interactive platform for indel analysis |
title_fullStr | SPAI: an interactive platform for indel analysis |
title_full_unstemmed | SPAI: an interactive platform for indel analysis |
title_short | SPAI: an interactive platform for indel analysis |
title_sort | spai: an interactive platform for indel analysis |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009558/ https://www.ncbi.nlm.nih.gov/pubmed/27585593 http://dx.doi.org/10.1186/s12864-016-2824-x |
work_keys_str_mv | AT hasanmohammadshabbir spaianinteractiveplatformforindelanalysis AT zhangliqing spaianinteractiveplatformforindelanalysis |