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SPAI: an interactive platform for indel analysis

BACKGROUND: Insertions and Deletions (Indels) are the most common form of structural variation in human genome. Indels not only contribute to genetic diversity but also cause diseases. Therefore assessing indels in human genome has become an interesting topic to the research community. This increasi...

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Detalles Bibliográficos
Autores principales: Hasan, Mohammad Shabbir, Zhang, Liqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009558/
https://www.ncbi.nlm.nih.gov/pubmed/27585593
http://dx.doi.org/10.1186/s12864-016-2824-x
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author Hasan, Mohammad Shabbir
Zhang, Liqing
author_facet Hasan, Mohammad Shabbir
Zhang, Liqing
author_sort Hasan, Mohammad Shabbir
collection PubMed
description BACKGROUND: Insertions and Deletions (Indels) are the most common form of structural variation in human genome. Indels not only contribute to genetic diversity but also cause diseases. Therefore assessing indels in human genome has become an interesting topic to the research community. This increasing interest on indel calling research has resulted into the development of a good number of indel calling tools. However, all of these tools are command line based and require expertise from Computer Science (CS) to execute them which makes it challenging for researchers from non-CS background. METHODS: In this paper, we describe an interactive platform named SPAI which stands for Single Platform for Analyzing Indels. RESULTS: Being a Graphical User Interface (GUI) tool, SPAI facilitates users to run several popular indel calling tools and perform several analyses on the indel calling results without knowing any command line programming. CONCLUSIONS: SPAI is written in Java and tested in Linux operating system.
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spelling pubmed-50095582016-09-08 SPAI: an interactive platform for indel analysis Hasan, Mohammad Shabbir Zhang, Liqing BMC Genomics Research BACKGROUND: Insertions and Deletions (Indels) are the most common form of structural variation in human genome. Indels not only contribute to genetic diversity but also cause diseases. Therefore assessing indels in human genome has become an interesting topic to the research community. This increasing interest on indel calling research has resulted into the development of a good number of indel calling tools. However, all of these tools are command line based and require expertise from Computer Science (CS) to execute them which makes it challenging for researchers from non-CS background. METHODS: In this paper, we describe an interactive platform named SPAI which stands for Single Platform for Analyzing Indels. RESULTS: Being a Graphical User Interface (GUI) tool, SPAI facilitates users to run several popular indel calling tools and perform several analyses on the indel calling results without knowing any command line programming. CONCLUSIONS: SPAI is written in Java and tested in Linux operating system. BioMed Central 2016-08-31 /pmc/articles/PMC5009558/ /pubmed/27585593 http://dx.doi.org/10.1186/s12864-016-2824-x Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Hasan, Mohammad Shabbir
Zhang, Liqing
SPAI: an interactive platform for indel analysis
title SPAI: an interactive platform for indel analysis
title_full SPAI: an interactive platform for indel analysis
title_fullStr SPAI: an interactive platform for indel analysis
title_full_unstemmed SPAI: an interactive platform for indel analysis
title_short SPAI: an interactive platform for indel analysis
title_sort spai: an interactive platform for indel analysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009558/
https://www.ncbi.nlm.nih.gov/pubmed/27585593
http://dx.doi.org/10.1186/s12864-016-2824-x
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