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Systematic analysis of phosphotyrosine antibodies recognizing single phosphorylated EPIYA-motifs in CagA of East Asian-type Helicobacter pylori strains

BACKGROUND: Highly virulent strains of the gastric pathogen Helicobacter pylori encode a type IV secretion system (T4SS) that delivers the effector protein CagA into gastric epithelial cells. Translocated CagA undergoes tyrosine phosphorylation by members of the oncogenic c-Src and c-Abl host kinase...

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Detalles Bibliográficos
Autores principales:	Lind, Judith, Backert, Steffen, Hoffmann, Rebecca, Eichler, Jutta, Yamaoka, Yoshio, Perez-Perez, Guillermo I., Torres, Javier, Sticht, Heinrich, Tegtmeyer, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009636/ https://www.ncbi.nlm.nih.gov/pubmed/27590005 http://dx.doi.org/10.1186/s12866-016-0820-6

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