Cargando…

The Mechanism of Long Non-coding RNA MEG3 for Neurons Apoptosis Caused by Hypoxia: Mediated by miR-181b-12/15-LOX Signaling Pathway

Objective: lncRNAs are recently thought to play a significant role in cellular homeostasis during pathological process of diseases by competing inhibiting miRNA function. The aim of present study was to assess the function of long non-coding RNA (lncRNA) MEG3 and its functional interaction with micr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiaomin, Hou, Lijing, Huang, Weiwei, Gao, Yuan, Lv, Xin, Tang, Jiyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009716/ https://www.ncbi.nlm.nih.gov/pubmed/27642276 http://dx.doi.org/10.3389/fncel.2016.00201

Ejemplares similares

Association between MEG3/miR-181b polymorphisms and risk of ischemic stroke
por: Han, Xuemei, et al.
Publicado: (2018)

Long non-coding RNA MEG3 promotes fibrosis and inflammatory response in diabetic nephropathy via miR-181a/Egr-1/TLR4 axis
por: Zha, Fangfang, et al.
Publicado: (2019)

Hydroperoxidation of Docosahexaenoic Acid by Human ALOX12 and pigALOX15-mini-LOX
por: Canyelles-Niño, Miquel, et al.
Publicado: (2023)

SNHG12 inhibits oxygen-glucose deprivation-induced neuronal apoptosis via the miR-181a-5p/NEGR1 axis
por: Yan, Yangtian, et al.
Publicado: (2020)

15-LOX metabolites and angiogenesis: angiostatic effect of 15(S)-HPETE involves induction of apoptosis in adipose endothelial cells
por: Soumya, Sasikumar J., et al.
Publicado: (2014)

miR-181c-5p Exacerbates Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Targeting PTPN4
por: Ge, Liang, et al.
Publicado: (2019)

The microRNA miR-181c controls microglia-mediated neuronal apoptosis by suppressing tumor necrosis factor
por: Zhang, Li, et al.
Publicado: (2012)

lncRNA MEG3 Downregulation Relieves Intracerebral Hemorrhage by Inhibiting Oxidative Stress and Inflammation in an miR-181b-Dependent Manner
por: Xie, Bo, et al.
Publicado: (2021)

Fucoidan-Mediated Inhibition of Fibrotic Properties in Oral Submucous Fibrosis via the MEG3/miR-181a/Egr1 Axis
por: Fang, Chih-Yuan, et al.
Publicado: (2022)

Brozopine Inhibits 15-LOX-2 Metabolism Pathway After Transient Focal Cerebral Ischemia in Rats and OGD/R-Induced Hypoxia Injury in PC12 Cells
por: Gao, Yuan, et al.
Publicado: (2020)

Sustained activation of 12/15 lipoxygenase (12/15 LOX) contributes to impaired renal recovery post ischemic injury in male SHR compared to females
por: Mohamed, Riyaz, et al.
Publicado: (2023)

Myeloid 12/15-LOX regulates B cell numbers and innate immune antibody levels in vivo
por: Lauder, Sarah N., et al.
Publicado: (2017)

Niraparib restrains prostate cancer cell proliferation and metastasis and tumor growth in mice by regulating the lncRNA MEG3/miR-181-5p/GATA6 pathway
por: Cheng, Ji, et al.
Publicado: (2023)

15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1α expression in human colon cancer cells
por: Wu, Yuanqing, et al.
Publicado: (2014)

MEG2 is regulated by miR-181a-5p and functions as a tumour suppressor gene to suppress the proliferation and migration of gastric cancer cells
por: Liu, Zhijian, et al.
Publicado: (2017)

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy
por: Miller, Bryan W, et al.
Publicado: (2015)

Long non-coding RNA CCAT1 promotes colorectal cancer progression by regulating miR-181a-5p expression
por: Shang, Anquan, et al.
Publicado: (2020)

Renal inhibition of miR-181a ameliorates 5-fluorouracil-induced mesangial cell apoptosis and nephrotoxicity
por: Liu, Xiao-Yun, et al.
Publicado: (2018)

Long non-coding RNA MEG3 knockdown alleviates hypoxia-induced injury in rat cardiomyocytes via the miR-325-3p/TRPV4 axis
por: Zhou, Ya, et al.
Publicado: (2021)

The conditional KO approach: Cre/Lox technology in human neurons
por: Patzke, Christopher, et al.
Publicado: (2016)

MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis
por: Wang, Anying, et al.
Publicado: (2019)

Arrival of the 15m ""Noell"" dipole in hall 181
por: Jean-Luc Caron
Publicado: (1997)

Arrival of the 15m ""Noell"" dipole in hall 181
por: Jean-Luc Caron
Publicado: (1997)

Arrival of the 15m ""Noell"" dipole in hall 181
por: Jean-Luc Caron
Publicado: (1997)

LncRNA MEG3 targeting miR-424-5p via MAPK signaling pathway mediates neuronal apoptosis in ischemic stroke
por: Xiang, Yanxiao, et al.
Publicado: (2020)

miR-181a Regulates Inflammation Responses in Monocytes and Macrophages
por: Xie, Weidong, et al.
Publicado: (2013)

SNP rs322931 (C>T) in miR-181b and rs7158663 (G>A) in MEG3 aggravate the inflammatory response of anal abscess in patients with Crohn’s disease
por: Zhong, Chaoxiang, et al.
Publicado: (2022)

MEG3 Regulates CSE-Induced Apoptosis by Regulating miR-421/DFFB Signal Axis
por: Bi, Hui, et al.
Publicado: (2023)

MiR-181a contributes to bufalin-induced apoptosis in PC-3 prostate cancer cells
por: Zhai, Xiao-feng, et al.
Publicado: (2013)

Induction of K562 Cell Apoptosis by As(4)S(4) via Down-Regulating miR181
por: Gong, Jiangjiang, et al.
Publicado: (2017)

Modulation of miR-181 influences dopaminergic neuronal degeneration in a mouse model of Parkinson’s disease
por: Stein, Colleen S., et al.
Publicado: (2022)

Characterization of Channelrhodopsin and Archaerhodopsin in Cholinergic Neurons of Cre-Lox Transgenic Mice
por: Hedrick, Tristan, et al.
Publicado: (2016)

Long non‐coding RNA MEG3 promotes autophagy and apoptosis of nasopharyngeal carcinoma cells via PTEN up‐regulation by binding to microRNA‐21
por: Lin, Liqiang, et al.
Publicado: (2020)

Knockdown of lncRNA SNHG14 alleviates LPS-induced inflammation and apoptosis of PC12 cells by regulating miR-181b-5p
por: Jiang, Hui, et al.
Publicado: (2021)

Let-7, Mir-98 and Mir-181 as Biomarkers for Cancer and Schizophrenia
por: Rizos, Emmanouil, et al.
Publicado: (2015)

Long Non-Coding RNA MEG3 in Cellular Stemness
por: Hsieh, Pei-Fang, et al.
Publicado: (2021)

Long Non-Coding RNA MEG3 in Metal Carcinogenesis
por: Zhang, Zhuo, et al.
Publicado: (2023)

12/15–Lipoxygenase debilitates mitochondrial health in intermittent hypobaric hypoxia induced neuronal damage: An in vivo study
por: Choudhary, Richa, et al.
Publicado: (2021)

Long-chain non-coding RNA GAS5 promotes cell autophagy by modulating the miR-181c-5p/ATG5 and miR-1192/ATG12 axes
por: Xu, Tao, et al.
Publicado: (2021)

Cracking the code of neuronal apoptosis and survival
por: Cavallaro, S
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_lr85tjuc9sj6amhdl26pathged