DNA compaction by the bacteriophage protein Cox studied on the single DNA molecule level using nanofluidic channels

The Cox protein from bacteriophage P2 forms oligomeric filaments and it has been proposed that DNA can be wound up around these filaments, similar to how histones condense DNA. We here use fluorescence microscopy to study single DNA–Cox complexes in nanofluidic channels and compare how the Cox homol...

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Detalles Bibliográficos
Autores principales: Frykholm, Karolin, Berntsson, Ronnie Per-Arne, Claesson, Magnus, de Battice, Laura, Odegrip, Richard, Stenmark, Pål, Westerlund, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009727/
https://www.ncbi.nlm.nih.gov/pubmed/27131370
http://dx.doi.org/10.1093/nar/gkw352

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