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The CRISPR RNA-guided surveillance complex in Escherichia coli accommodates extended RNA spacers

Bacteria and archaea acquire resistance to foreign genetic elements by integrating fragments of foreign DNA into CRISPR (clustered regularly interspaced short palindromic repeats) loci. In Escherichia coli, CRISPR-derived RNAs (crRNAs) assemble with Cas proteins into a multi-subunit surveillance com...

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Detalles Bibliográficos
Autores principales:	Luo, Michelle L., Jackson, Ryan N., Denny, Steven R., Tokmina-Lukaszewska, Monika, Maksimchuk, Kenneth R., Lin, Wayne, Bothner, Brian, Wiedenheft, Blake, Beisel, Chase L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009729/ https://www.ncbi.nlm.nih.gov/pubmed/27174938 http://dx.doi.org/10.1093/nar/gkw421

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