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Perpetuating the homing endonuclease life cycle: identification of mutations that modulate and change I-TevI cleavage preference
Homing endonucleases are sequence-tolerant DNA endonucleases that act as mobile genetic elements. The ability of homing endonucleases to cleave substrates with multiple nucleotide substitutions suggests a high degree of adaptability in that changing or modulating cleavage preference would require re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009752/ https://www.ncbi.nlm.nih.gov/pubmed/27387281 http://dx.doi.org/10.1093/nar/gkw614 |