Cargando…

Zic2 is an enhancer-binding factor required for embryonic stem cell specification

The Zinc finger protein of the cerebellum 2 (Zic2) is one of the vertebrate homologs of the Drosophila pair-rule gene odd-paired (opa). Our molecular and biochemical studies demonstrate that Zic2 preferentially binds to transcriptional enhancers and is required for the regulation of gene expression...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Zhuojuan, Gao, Xin, Lin, Chengqi, Smith, Edwin, Marshall, Stacy, Swanson, Selene K., Florens, Laurence, Washburn, Michael P., Shilatifard, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009765/ https://www.ncbi.nlm.nih.gov/pubmed/25699711 http://dx.doi.org/10.1016/j.molcel.2015.01.007

Ejemplares similares

Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity
por: Luo, Zhuojuan, et al.
Publicado: (2016)

Expression of the zic1, zic2, zic3, and zic4 genes in early chick embryos
por: McMahon, Ariel R, et al.
Publicado: (2010)

Striking a balance: regulation of transposable elements by Zfp281 and Mll2 in mouse embryonic stem cells
por: Dai, Qian, et al.
Publicado: (2017)

β-Catenin/Tcf7l2–dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer
por: Zhao, Zibo, et al.
Publicado: (2019)

Lentiviral Vpx Accessory Factor Targets VprBP/DCAF1 Substrate Adaptor for Cullin 4 E3 Ubiquitin Ligase to Enable Macrophage Infection
por: Srivastava, Smita, et al.
Publicado: (2008)

Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexes
por: Lee, Kenneth K, et al.
Publicado: (2009)

An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells
por: Cao, Kaixiang, et al.
Publicado: (2018)

Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling
por: Oh, Seunghee, et al.
Publicado: (2020)

The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
por: Vilhais-Neto, Gonçalo C., et al.
Publicado: (2017)

Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum
por: Frank, Christopher L., et al.
Publicado: (2015)

Phase separation, transcriptional elongation control, and human diseases
por: Guo, Chenghao, et al.
Publicado: (2021)

Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy
por: Hopfner, Franziska, et al.
Publicado: (2022)

A novel conserved enhancer at zebrafish zic3 and zic6 loci drives neural expression
por: Minhas, Rashid, et al.
Publicado: (2019)

Zic Family Member 2 (ZIC2): a Potential Diagnostic and Prognostic Biomarker for Pan-Cancer
por: Lv, Zhengtong, et al.
Publicado: (2021)

The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells
por: Hu, Deqing, et al.
Publicado: (2013)

Zic2 hypomorphic mutant mice as a schizophrenia model and ZIC2 mutations identified in schizophrenia patients
por: Hatayama, Minoru, et al.
Publicado: (2011)

The TDH-GCN5L1-Fbxo15-KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells
por: Donato, Valerio, et al.
Publicado: (2017)

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
por: Hrecka, Kasia, et al.
Publicado: (2011)

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity
por: Dykes, Iain M., et al.
Publicado: (2018)

Analysis of RNA-Seq datasets reveals enrichment of tissue-specific splice variants for nuclear envelope proteins
por: Capitanchik, Charlotte, et al.
Publicado: (2018)

Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets
por: García-Frigola, Cristina, et al.
Publicado: (2010)

SUMOylation Potentiates ZIC Protein Activity to Influence Murine Neural Crest Cell Specification
por: Bellchambers, Helen M., et al.
Publicado: (2021)

Systematized reporter assays reveal ZIC protein regulatory abilities are Subclass-specific and dependent upon transcription factor binding site context
por: Ahmed, Jehangir N., et al.
Publicado: (2020)

Changing Faces of Transcriptional Regulation Reflected by Zic3
por: Winata, Cecilia Lanny, et al.
Publicado: (2015)

An Evolutionarily Conserved Mesodermal Enhancer in Vertebrate Zic3
por: Odaka, Yuri S., et al.
Publicado: (2018)

Transcriptional expression of ZICs as an independent indicator of survival in gliomas
por: Han, Zhaocheng, et al.
Publicado: (2021)

Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes
por: Lee, Kenneth K, et al.
Publicado: (2011)

The Enok acetyltransferase complex interacts with Elg1 and negatively regulates PCNA unloading to promote the G1/S transition
por: Huang, Fu, et al.
Publicado: (2016)

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169
por: R. Menon, Vijay, et al.
Publicado: (2019)

Expression of ZIC family genes in meningiomas and other brain tumors
por: Aruga, Jun, et al.
Publicado: (2010)

Heterotaxy-spectrum heart defects in Zic3 hypomorphic mice
por: Haaning, Allison M., et al.
Publicado: (2013)

ZIC3 Controls the Transition from Naive to Primed Pluripotency
por: Yang, Shen-Hsi, et al.
Publicado: (2019)

AR-regulated ZIC5 contributes to the aggressiveness of prostate cancer
por: Tan, Yi-Fan, et al.
Publicado: (2022)

Requirements for human embryonic stem cells
por: Hao, Jie, et al.
Publicado: (2020)

The human cytoplasmic dynein interactome reveals novel activators of motility
por: Redwine, William B, et al.
Publicado: (2017)

Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation
por: Sze, Christie C., et al.
Publicado: (2017)

β-Catenin and Associated Proteins Regulate Lineage Differentiation in Ground State Mouse Embryonic Stem Cells
por: Tao, Fang, et al.
Publicado: (2020)

Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans
por: Layden, Michael J, et al.
Publicado: (2010)

The role of Zic transcription factors in regulating hindbrain retinoic acid signaling
por: Drummond, Danna L, et al.
Publicado: (2013)

The Zic family homologue Odd-paired regulates Alk expression in Drosophila
por: Mendoza-García, Patricia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_gsrg5p2ii2enrlride0t2u5rgv