miR‐132 loss de‐represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain

microRNA‐132 (miR‐132) is involved in prosurvival, anti‐inflammatory and memory‐promoting functions in the nervous system and has been found consistently downregulated in Alzheimer's disease (AD). Whether and how miR‐132 deficiency impacts AD pathology remains, however, unaddressed. We show her...

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Detalles Bibliográficos
Autores principales: Salta, Evgenia, Sierksma, Annerieke, Vanden Eynden, Elke, De Strooper, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009807/
https://www.ncbi.nlm.nih.gov/pubmed/27485122
http://dx.doi.org/10.15252/emmm.201606520

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