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Predicting essential proteins based on subcellular localization, orthology and PPI networks

BACKGROUND: Essential proteins play an indispensable role in the cellular survival and development. There have been a series of biological experimental methods for finding essential proteins; however they are time-consuming, expensive and inefficient. In order to overcome the shortcomings of biologi...

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Detalles Bibliográficos
Autores principales: Li, Gaoshi, Li, Min, Wang, Jianxin, Wu, Jingli, Wu, Fang-Xiang, Pan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009824/
https://www.ncbi.nlm.nih.gov/pubmed/27586883
http://dx.doi.org/10.1186/s12859-016-1115-5