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Human CD8+ T cells mediate protective immunity induced by a human malaria vaccine in human immune system mice
A number of studies have shown that CD8+ T cells mediate protective anti-malaria immunity in a mouse model. However, whether human CD8+ T cells play a role in protection against malaria remains unknown. We recently established human immune system (HIS) mice harboring functional human CD8+ T cells (H...
Autores principales: | Li, Xiangming, Huang, Jing, Zhang, Min, Funakoshi, Ryota, Sheetij, Dutta, Spaccapelo, Roberta, Crisanti, Andrea, Nussenzweig, Victor, Nussenzweig, Ruth S., Tsuji, Moriya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009892/ https://www.ncbi.nlm.nih.gov/pubmed/27502569 http://dx.doi.org/10.1016/j.vaccine.2016.08.006 |
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