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Soluble ST2 and Galectin-3: What We Know and Don’t Know Analytically
The proteins soluble ST2 (sST2) and galectin-3 are currently gaining mounting interest as candidate biomarkers in cardiac disease. Both, sST2 and galectin-3 have been included in the 2013 ACCF/AHA guideline for additive risk stratification of patients with acute and chronic heart failure. The aim of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Communications and Publications Division (CPD) of the IFCC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009947/ https://www.ncbi.nlm.nih.gov/pubmed/27683536 |
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author | Mueller, Thomas Dieplinger, Benjamin |
author_facet | Mueller, Thomas Dieplinger, Benjamin |
author_sort | Mueller, Thomas |
collection | PubMed |
description | The proteins soluble ST2 (sST2) and galectin-3 are currently gaining mounting interest as candidate biomarkers in cardiac disease. Both, sST2 and galectin-3 have been included in the 2013 ACCF/AHA guideline for additive risk stratification of patients with acute and chronic heart failure. The aim of this review is to provide information on analytical considerations of measuring circulating sST2 and galectin-3 including knowledge on in vitro stability, biological variation and reference ranges of both analytes. |
format | Online Article Text |
id | pubmed-5009947 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The Communications and Publications Division (CPD) of the IFCC |
record_format | MEDLINE/PubMed |
spelling | pubmed-50099472016-09-28 Soluble ST2 and Galectin-3: What We Know and Don’t Know Analytically Mueller, Thomas Dieplinger, Benjamin EJIFCC Research Article The proteins soluble ST2 (sST2) and galectin-3 are currently gaining mounting interest as candidate biomarkers in cardiac disease. Both, sST2 and galectin-3 have been included in the 2013 ACCF/AHA guideline for additive risk stratification of patients with acute and chronic heart failure. The aim of this review is to provide information on analytical considerations of measuring circulating sST2 and galectin-3 including knowledge on in vitro stability, biological variation and reference ranges of both analytes. The Communications and Publications Division (CPD) of the IFCC 2016-07-01 /pmc/articles/PMC5009947/ /pubmed/27683536 Text en Copyright © 2016 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Mueller, Thomas Dieplinger, Benjamin Soluble ST2 and Galectin-3: What We Know and Don’t Know Analytically |
title | Soluble ST2 and Galectin-3: What We Know and Don’t Know Analytically |
title_full | Soluble ST2 and Galectin-3: What We Know and Don’t Know Analytically |
title_fullStr | Soluble ST2 and Galectin-3: What We Know and Don’t Know Analytically |
title_full_unstemmed | Soluble ST2 and Galectin-3: What We Know and Don’t Know Analytically |
title_short | Soluble ST2 and Galectin-3: What We Know and Don’t Know Analytically |
title_sort | soluble st2 and galectin-3: what we know and don’t know analytically |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009947/ https://www.ncbi.nlm.nih.gov/pubmed/27683536 |
work_keys_str_mv | AT muellerthomas solublest2andgalectin3whatweknowanddontknowanalytically AT dieplingerbenjamin solublest2andgalectin3whatweknowanddontknowanalytically |