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Asymmetric Hydroarylation of Vinylarenes Using a Synergistic Combination of CuH and Pd Catalysis
[Image: see text] Detailed in this Communication is the enantioselective synthesis of 1,1-diarylalkanes, a structure found in a range of pharmaceutical drug agents and natural products, through the employment of copper(I) hydride and palladium catalysis. Judicious choice of ligand for both Cu and Pd...
Autores principales: | Friis, Stig D., Pirnot, Michael T., Buchwald, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2016
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010014/ https://www.ncbi.nlm.nih.gov/pubmed/27346525 http://dx.doi.org/10.1021/jacs.6b04566 |
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