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Development of a Method for the N-Arylation of Amino Acid Esters with Aryl Triflates
[Image: see text] A general method for the N-arylation of amino acid esters with aryl triflates is described. Both α- and β-amino acid esters, including methyl, tert-butyl, and benzyl esters, are viable substrates. Reaction optimization was carried out by design of experiment (DOE) analysis using JM...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010016/ https://www.ncbi.nlm.nih.gov/pubmed/27498618 http://dx.doi.org/10.1021/acs.orglett.6b02082 |