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Shigella flexneri suppresses NF-kB activation by inhibiting linear ubiquitin chain ligation

The Linear Ubiquitin chain Assembly Complex (LUBAC) is a multimeric E3 ligase that catalyzes M1- or linear ubiquitination of activated immune receptor signaling complexes (RSCs). While mutations that disrupt linear ubiquitin assembly lead to complex disease pathologies including immunodeficiency and...

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Detalles Bibliográficos
Autores principales:	de Jong, Maarten F., Liu, Zixu, Chen, Didi, Alto, Neal M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010086/ https://www.ncbi.nlm.nih.gov/pubmed/27572974 http://dx.doi.org/10.1038/nmicrobiol.2016.84

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