ALDH1A1 induces resistance to CHOP in diffuse large B-cell lymphoma through activation of the JAK2/STAT3 pathway

Increasing evidence has shown that aldehyde dehydrogenase 1A1 (ALDH1A1), a detoxifying enzyme, is responsible for chemoresistance in a variety of tumors. Although the majority of patients with diffuse large B-cell lymphoma (DLBCL) can be cured with cyclophosphamide, doxorubicin, vincristine, and pre...

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Detalles Bibliográficos
Autores principales: Jiang, Jinqiong, Liu, Yiping, Tang, Youhong, Li, Li, Zeng, Ruolan, Zeng, Shan, Zhong, Meizuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010157/
https://www.ncbi.nlm.nih.gov/pubmed/27621650
http://dx.doi.org/10.2147/OTT.S107957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010157/
https://www.ncbi.nlm.nih.gov/pubmed/27621650
http://dx.doi.org/10.2147/OTT.S107957

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