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ALDH1A1 induces resistance to CHOP in diffuse large B-cell lymphoma through activation of the JAK2/STAT3 pathway
Increasing evidence has shown that aldehyde dehydrogenase 1A1 (ALDH1A1), a detoxifying enzyme, is responsible for chemoresistance in a variety of tumors. Although the majority of patients with diffuse large B-cell lymphoma (DLBCL) can be cured with cyclophosphamide, doxorubicin, vincristine, and pre...
Autores principales: | Jiang, Jinqiong, Liu, Yiping, Tang, Youhong, Li, Li, Zeng, Ruolan, Zeng, Shan, Zhong, Meizuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010157/ https://www.ncbi.nlm.nih.gov/pubmed/27621650 http://dx.doi.org/10.2147/OTT.S107957 |
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