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Verteporfin, a suppressor of YAP–TEAD complex, presents promising antitumor properties on ovarian cancer
Yes-associated protein (YAP) is a key transcriptional coactivator of Hippo pathway and has been shown to be an oncoprotein in ovarian cancer (OC). Verteporfin (VP), clinically used in photodynamic therapy for neovascular macular degeneration, has been recently proven to be a suppressor of YAP–TEAD c...
Autores principales: | Feng, Juntao, Gou, Jinhai, Jia, Jia, Yi, Tao, Cui, Tao, Li, Zhengyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010158/ https://www.ncbi.nlm.nih.gov/pubmed/27621651 http://dx.doi.org/10.2147/OTT.S109979 |
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