Cargando…

Effect of DcR3-specific siRNA on cell growth suppression and apoptosis induction in glioma cells via affecting ERK and AKT

BACKGROUND: Previously, we found that the expression of decoy receptor 3 (DcR3) in gliomas was significantly upregulated compared to normal brain tissues. However, the effect of DcR3-specific small interfering RNA (siRNA) on cell biological function of glioma cells remains incompletely understood. O...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yu, Huang, Suning, Leng, Yuhua, Chen, Xin, Liu, Tiantian, Wang, Hanlin, Wei, Fanglin, Luo, Dianzhong, Chen, Gang, Wei, Zhuxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010168/ https://www.ncbi.nlm.nih.gov/pubmed/27621648 http://dx.doi.org/10.2147/OTT.S108395

Ejemplares similares

Overexpression of DcR3 and Its Significance on Tumor Cell Differentiation and Proliferation in Glioma
por: Huang, Suning, et al.
Publicado: (2014)

The siRNA silencing of DcR3 expression induces Fas ligand-mediated apoptosis in HepG2 cells
por: Zhao, Tuanjie, et al.
Publicado: (2018)

Research Progress of DcR3 in the Diagnosis and Treatment of Sepsis
por: Su, Jingqian, et al.
Publicado: (2023)

GATA4 and DcR1 methylation in glioblastomas
por: Vaitkienė, Paulina, et al.
Publicado: (2013)

Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference
por: Tants, Jan-Niklas, et al.
Publicado: (2017)

Amelioration of amyloid-β-induced deficits by DcR3 in an Alzheimer’s disease model
por: Liu, Yi-Ling, et al.
Publicado: (2017)

DcR3, a new biomarker for sepsis, correlates with infection severity and procalcitonin
por: Gao, Liqin, et al.
Publicado: (2017)

Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis
por: Liang, Chaojie, et al.
Publicado: (2017)

TIPE Regulates DcR3 Expression and Function by Activating the PI3K/AKT Signaling Pathway in CRC
por: Zhong, Mengya, et al.
Publicado: (2021)

Membrane expression of TRAIL receptors DR4, DR5, DcR1 and DcR2 in the normal endometrium, atypical endometrial hyperplasia and endometrioid adenocarcinoma: a tissue microarray study
por: Gottwald, Leszek, et al.
Publicado: (2013)

DcR3 combined with hematological traits serves as a valuable biomarker for the diagnosis of cancer metastasis
por: Li, Junxin, et al.
Publicado: (2017)

Endoscopic DCR vs External DCR: What's Best in the Acute Setting?
por: Amadi, Arash J.
Publicado: (2017)

The Network of Pro-Inflammatory Factors CD147, DcR3, and IL33 in the Development of Kawasaki Disease
por: Qi, Yanqi, et al.
Publicado: (2021)

‘Decoy’ and ‘non-decoy’ functions of DcR3 promote malignant potential in human malignant fibrous histiocytoma cells
por: TODA, MITSUNORI, et al.
Publicado: (2013)

Up-regulation of DcR3 in microbial toxins-stimulated HUVECs involves NF-κB signalling
por: Hou, Yanqiang, et al.
Publicado: (2018)

DcR3 gene polymorphisms are associated with sporadic breast infiltrating ductal carcinoma in Northeast Chinese women
por: Fu, Zhenkun, et al.
Publicado: (2016)

Dendritic cells engineered to secrete anti-DcR3 antibody augment cytotoxic T lymphocyte response against pancreatic cancer in vitro
por: Chen, Jiang, et al.
Publicado: (2017)

Decoy Receptor 3 (DcR3) as a Biomarker of Tumor Deterioration in Female Reproductive Cancers: A Meta-Analysis
por: Jiang, Mengtong, et al.
Publicado: (2016)

Absolute quantification of DcR3 and GDF15 from human serum by LC-ESI MS
por: Lancrajan, Ioana, et al.
Publicado: (2015)

Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis
por: Vindrieux, David, et al.
Publicado: (2011)

Upregulated TRAIL and Reduced DcR2 Mediate Apoptosis of Decidual PMN-MDSC in Unexplained Recurrent Pregnancy Loss
por: Li, Congcong, et al.
Publicado: (2020)

Expression and clinicopathological implication of DcR3 in lung cancer tissues: a tissue microarray study with 365 cases
por: Zhang, Yu, et al.
Publicado: (2016)

Anti‐oral cancer effects of triptolide by downregulation of DcR3 in vitro, in vivo, and in preclinical patient‐derived tumor xenograft model
por: Yang, Cheng‐Yu, et al.
Publicado: (2018)

MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells
por: Badiga, Aruna Venkata, et al.
Publicado: (2011)

Intracranially injectable multi-siRNA nanomedicine for the inhibition of glioma stem cells
por: Manju, Cheripelil Abraham, et al.
Publicado: (2021)

siRNA-Mediated Suppression of Synuclein γ Inhibits MDA-MB-231 Cell Migration and Proliferation by Downregulating the Phosphorylation of AKT and ERK
por: He, Jingsong, et al.
Publicado: (2014)

Identification and preclinical evaluation of the small molecule, NSC745887, for treating glioblastomas via suppressing DcR3-associated signaling pathways
por: Fann, Li-Yun, et al.
Publicado: (2017)

TRAIL and DcR1 Expressions Are Differentially Regulated in the Pancreatic Islets of STZ- versus CY-Applied NOD Mice
por: Dirice, Ercument, et al.
Publicado: (2011)

Decoy receptor 3 (DcR3) overexpression predicts the prognosis and pN2 in pancreatic head carcinoma
por: Zhou, Jian, et al.
Publicado: (2014)

Hypermethylation of DcR1 Gene-based Biomarker in Non-invasive Cancer Screening of Vietnamese Cervical Cancer Patients
por: TRUONG, Phuong Kim, et al.
Publicado: (2018)

A new approach to endoscopic DCR
por: Singh, Amit Pal, et al.
Publicado: (2015)

Retraction: MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells
Publicado: (2020)

Therapeutic siRNA: state of the art
por: Hu, Bo, et al.
Publicado: (2020)

Modified external revision-DCR in previous failed endonasal, transcanalicular or external-DCR: technical strategy and teaching Pearls for success
por: Evereklioglu, Cem, et al.
Publicado: (2023)

DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway
por: Ge, Hua, et al.
Publicado: (2018)

Specific elevation of DcR3 in sera of sepsis patients and its potential role as a clinically important biomarker of sepsis()
por: Kim, Sunghee, et al.
Publicado: (2012)

Role of TGFβ3-Smads-Sp1 axis in DcR3-mediated immune escape of hepatocellular carcinoma
por: Zhu, Hui-fang, et al.
Publicado: (2019)

DcR3 induces epithelial-mesenchymal transition through activation of the TGF-β3/SMAD signaling pathway in CRC
por: Liu, Yan-Ping, et al.
Publicado: (2016)

The therapeutic effect in gliomas of nanobubbles carrying siRNA combined with ultrasound-targeted destruction
por: Cai, Wenbin, et al.
Publicado: (2018)

Self-Assembled DNA Nanostructure as a Carrier for Targeted siRNA Delivery in Glioma Cells
por: Zhou, Yanghao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b5mo9aqejivnqsgiedvpn20ats