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Establishment of IL-7 Expression Reporter Human Cell Lines, and Their Feasibility for High-Throughput Screening of IL-7-Upregulating Chemicals
Interleukin-7 (IL-7) is a cytokine essential for T cell homeostasis, and is clinically important. However, the regulatory mechanism of IL-7 gene expression is not well known, and a systematic approach to screen chemicals that regulate IL-7 expression has not yet been developed. In this study, we att...
Autores principales: | Cho, Yeon Sook, Kim, Byung Soo, Sim, Chan Kyu, Kim, Inki, Lee, Myeong Sup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010243/ https://www.ncbi.nlm.nih.gov/pubmed/27589392 http://dx.doi.org/10.1371/journal.pone.0161899 |
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