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KSP inhibitor SB743921 inhibits growth and induces apoptosis of breast cancer cells by regulating p53, Bcl-2, and DTL

Kinesin spindle protein (KSP) is a microtubule-associated motor protein that is specifically expressed by mitosis cells. It is highly expressed in various types of tumors including hematomalignances and solid tumors. Chemical KSP inhibition has become a novel strategy in the development of anticance...

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Detalles Bibliográficos
Autores principales:	Zhu, Li, Xiao, Fengjun, Yu, Yue, Wang, Hua, Fang, Min, Yang, Yuefeng, Sun, Huiyan, Wang, Lisheng, Sheng, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Preclinical Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010280/ https://www.ncbi.nlm.nih.gov/pubmed/27379929 http://dx.doi.org/10.1097/CAD.0000000000000402

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