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The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines
INTRODUCTION: A number of leptin receptor antagonists have been synthesised for therapeutic use, with pre-clinical tests suggesting their future use in anticancer therapy. To our knowledge, there are no data concerning the possible application of leptin receptor blockers in ovarian cancer. METHODS:...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010610/ https://www.ncbi.nlm.nih.gov/pubmed/27480179 http://dx.doi.org/10.1007/s00280-016-3113-8 |