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The molecular mechanism of action of superactive human leptin antagonist (SHLA) and quadruple leptin mutein Lan-2 on human ovarian epithelial cell lines

INTRODUCTION: A number of leptin receptor antagonists have been synthesised for therapeutic use, with pre-clinical tests suggesting their future use in anticancer therapy. To our knowledge, there are no data concerning the possible application of leptin receptor blockers in ovarian cancer. METHODS:...

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Detalles Bibliográficos
Autores principales: Fiedor, Elżbieta, Gregoraszczuk, Ewa Łucja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010610/
https://www.ncbi.nlm.nih.gov/pubmed/27480179
http://dx.doi.org/10.1007/s00280-016-3113-8