Cargando…
An analytical workflow for accurate variant discovery in highly divergent regions
BACKGROUND: Current variant discovery methods often start with the mapping of short reads to a reference genome; yet, their performance deteriorates in genomic regions where the reads are highly divergent from the reference sequence. This is particularly problematic for the human leukocyte antigen (...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010666/ https://www.ncbi.nlm.nih.gov/pubmed/27590916 http://dx.doi.org/10.1186/s12864-016-3045-z |